ECBM E6070 Computing with Brain Circuits of Model Organisms
|Lecturer:||Professor Aurel A. Lazar|
|Office hours:||By appointment, Room 819 Schapiro|
|E-mail address:||aurel "at" ee.columbia.edu|
|Class Web Site:||Offered by CourseWorks|
|Day and Time:||Mondays, 7:00 PM - 9:30 PM|
|Credits for course:||3 points|
|Prerequisites||BMEB W4020 Computational Neuroscience: Circuits in the Brain and/or ECBM E4040 Neural Networks and Deep Learning. Python programming experience or the instructor’s approval. Prior exposure to interactive computing (e.g., JupyterLab) is a plus.|
|Description:||The Functional Map of the Fruit Fly Brain
Modeling the brain of model organisms with an emphasis on the fruit fly. The Fruit Fly Brain Observatory. Structural modeling of the Drosophila brain using cell-type, connectome, synaptome and activity maps. Building the functional map of the fruit fly brain with FlyBrainLab.
From Sensory Coding in Early Vision to Directing Movement
Pathways and Circuits of the Early Visual System. Molecular Transduction and Spatio-Temporal Encoding in the Drosophila Retina. Contrast Gain Control in the Photoreceptor and Amacrine Cell Layer. Canonical Motion Detection Circuits. The Functional Role of the Central Complex. Canonical Navigation Circuits in the Central Complex.
From Odorant Transduction to Learning and Memory in Early Olfaction
Pathways and Circuits of the Early Olfactory System. Molecular Transduction and Combinatorial Encoding in the Drosophila Antenna. Predictive Coding in the Antennal Lobe. The Functional Role of the Mushroom Body. Canonical Circuits for Associative Learning and Memory in the Mushroom Body.
Projects in Python
|RCMD Text:|| Lectures Notes will be made available.
|Project(s)||2 individual projects|
|Midterm exam:||Project I: TBA|
|Final Exam:||Project II: TBA|
|Grading||Midterm Project (50%) and Final Project (50%)|
|Hardware requirements:||Laptop for demos.|