Odorant Transduction and Combinatorial Encoding in the Early Olfactory System


We briefly describe below our work on modeling odorant transduction and combinatorial encoding of the olfactory sensory neurons.

The antenna and the antenna lobe of the early olfactory system of the fruit fly brain are, respectively, described by the publications below. Electrophysiology recordings are available at the Fruit Fly Brain Observatory.

  1. Aurel A. Lazar and Chung-Heng Yeh, Predictive Coding in the Drosophila Antennal Lobe, BMC Neuroscience 2019, 20 (Suppl 1): P346 , 28th Annual Computational Neuroscience Meeting, July 13-17, 2019, Barcelona, Spain.
  2. Aurel A. Lazar and Chung-Heng Yeh, A Molecular Odorant Transduction Model and the Complexity of Spatio-Temporal Encoding in the Drosophila Antenna, PLOS Computational Biology, Volume 16, Number 4, April 2020.
  3. Aurel A. Lazar, Tingkai Liu, and Chung-Heng Yeh, An Odorant Encoding Machine for Sampling, Reconstruction and Robust Representation of Odorant Identity, ICASSP 2020, May 4-8, 2020, Barcelona, Spain.



The Bionet Group is supported by grants from



  NSF   NIH   AFOSR   DARPA



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