Fruit Fly Brain Observatory


The Fruit Fly Brain Observatory is an open collaborative ecosystem that provides

  • a hub for storing and integrating fruit fly brain research data from multiple data sources worldwide,
  • a unified repository of tools and methods to build, emulate and compare fruit fly brain models in health and disease, and
  • an open framework for fruit fly brain data processing and model execution.
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The FFBO assembles cell type, connectome, synaptome and activity maps within a single ecosystem that benefits three groups of stakeholders:

  • neurobiologists and neurogenetists,
  • computational and theoretical neuroscientists, and
  • computer scientists/engineers.

The FFBO dramatically increases the pace of discovery by enabling neurobiologists and computational neuroscientists alike to generate and test new hypotheses, by interrogating, visualizing and simulating the fruit fly brain at different scales, from neural circuits to neuropils and ultimately the entire brain. Learn more.

1. N. H. Ukani, C.-H. Yeh, A. Tomkins, Y. Zhou, D. Florescu, C. L. Ortiz, Y.-C. Huang, C.-T. Wang, P. Richmond, C.-C. Lo, D. Coca, A.-S. Chiang, and A. A. Lazar, Fruit Fly Brain Observatory: from Structure to Function, Neurokernel Request for Comments, Neurokernel RFC #7, December 2016.

2. N. H. Ukani, C.-H. Yeh, A. Tomkins, Y. Zhou, D. Florescu, C. L. Ortiz, Y.-C. Huang, C.-T. Wang, P. Richmond, C.-C. Lo, D. Coca, A.-S. Chiang, and A. A. Lazar, The Fruit Fly Brain Observatory: from Structure to Function, Computational and Systems Neuroscience Meeting, February 2017, Salt Lake City, UT.

3. N. H. Ukani, C.-H. Yeh, A. Tomkins, Y. Zhou, D. Florescu, C. L. Ortiz, Y.-C. Huang, C.-T. Wang, M. K. Turkcan, T. Liu, P. Richmond, C.-C. Lo, D. Coca, A.-S. Chiang, and A. A. Lazar, The Fruit Fly Brain Observatory: From Structure to Function, bioRxiv, Volume 580290, March 2019.


The Bionet Group is supported by grants from



  NSF   NIH   AFOSR   DARPA



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